General Information

  • ID:  hor002549
  • Uniprot ID:  A0A6I8TEZ7
  • Protein name:  NPLP-1-6
  • Gene name:  5565029
  • Organism:  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  NIQSLLRTGMLPSIAP
  • Length:  16
  • Propeptide:  MGNFKMLLPPKLFLRILMLLFLIVHDASSQYTDGNRRLKPCELESLLRDLTYPEEGYEMHAAALRNQLRHILEREPTDGAYQSLDEYGSYENTGPYEDKRSYRSLLRDGATFGKRNLGSLARAGLLRTPSTDYLKRSIATLAKNGQLPASREPDSEEAASAGGWNDEKRNLASARASGYMLNGKRNIASLARKYELPGKRNIQSLLRTGMLPSIAPKRNMQSLARDNSLPHFAGAAAQESKRNIQTLVRDWNLPRQQSMAADNEKRNIQSLKNAQGQGGGSSSGGRKKRELYYDDETLDDSAPEILEPVYQSSPLDYEELMEAMNEAYTPYYNSPADNHLEQKRYLGSLARAGHLHRYHRFYKRAPMGSFDGLYGNDDDDDNGTGSDNYEGEDRHKRKHASKDVLDDDNDDDDDNDEDYEPRSSVALHIPQKRHLGSIIRSGWMPSFRPSRTTGRFSRSGRARSSFTPNPSDYDNLSPAFVDDATALATAADFEQHQQQQQHPLPSAAGELPVYSPRGVLRHPELPHYTGAAFGNRPRMYAGGLPEEYLDSSSETSARPSNPFYTEDEFRCAARLRKLLYYLKKQYYLDNKYIQSVYGRNPVRY
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A6I8TEZ7-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002549_AF2.pdbhor002549_ESM.pdb

Physical Information

Mass: 197879 Formula: C75H131N21O22S
Absent amino acids: CDEFHKVWY Common amino acids: L
pI: 10.55 Basic residues: 1
Polar residues: 5 Hydrophobic residues: 6
Hydrophobicity: 41.88 Boman Index: -677
Half-Life: 1.4 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 128.13
Instability Index: 10714.38 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  20163154
  • Title:  Neuropeptidomics of the Mosquito Aedes Aegypti